AcipHex
Brand
name:AcipHex
Pronounced: ASS-ih-fex
Generic name: Rabeprazole sodium
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Why
is AcipHex prescribed?
AcipHex
blocks acid production in the stomach. It is prescribed for
the short-term (4 to 8 weeks) treatment of sores and inflammation
in the upper digestive canal (esophagus). This condition, known
as gastroesophageal reflux disease (GERD), is caused by the
backflow of stomach acid into the esophagus over a prolonged
period of time. Because GERD can be chronic, your doctor may
continue to prescribe AcipHex to prevent a relapse after your
initial course of treatment.
Rabeprazole
can also be prescribed for the short-term (up to 4 weeks) treatment
of duodenal ulcers (ulcers that form just outside the stomach
at the top of the small intestine), and for Zollinger-Ellison
Syndrome, a disease which causes the stomach to produce too
much acid. The drug is classified as a "proton pump inhibitor."
It works by blocking a specific enzyme essential to the production
of stomach acid. It begins reducing acid within an hour of administration.
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Most
important fact about AcipHex
AcipHex
will work even if your symptoms are caused by a serious condition
such as stomach cancer. For that reason, doctors are warned
to rule out cancer whenever prescribing this drug.
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How
should you take AcipHex?
Take
Rabeprazole once a day. Swallow the tablet whole; it should
not be crushed, chewed, or split. You can continue taking antacids
during AcipHex therapy.
—If
you miss a dose…
Take
it as soon as you remember. If it is almost time for your next
dose, skip the one you missed and go back to your regular schedule.
Do not take two doses at once.
—Storage
information…
AcipHex
should be stored at room temperature and protected from moisture.
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What
side effects may occur?
Side
effects cannot be anticipated. If any develop or change in intensity,
tell your doctor as soon as possible. Only your doctor can determine
if it is safe for you to continue taking AcipHex.
Headache
is the most common side effect of AcipHex, striking two people
out of 100.
Less
common side effects may include:
Abdominal pain, abnormal dreams, abnormal stools, abnormal vision,
allergic reaction, anxiety, arthritis, asthma, belching, bladder
inflammation, bone pain, breakthrough menstrual bleeding, bruising,
bursitis, cataract, chest pain, chills, constipation, convulsion,
decreased sex drive, dehydration, depression, diarrhea, difficult
breathing, difficult periods, dizziness, dry eyes, dry mouth,
ear infection, fainting, fatigue, fever, fluid retention, frequent
urination, gallbladder disease, gas, glaucoma, gout, gum inflammation,
hair loss, heart attack, hiccup, high blood pressure, hives,
hyperventilation, increased appetite, inflammation of the esophagus,
inflammation of the pancreas, insomnia, intestinal inflammation,
irregular heartbeat, itching, joint disease, kidney stone, laryngitis,
leg cramps, loss of appetite, lymph node disease, migraine,
mouth inflammation, mouth sores, muscle pain, nausea, nerve
pain, nervous system disorder, nervousness, nosebleed, overactive
thyroid, painful urination, pins and needles sensation, pounding
heartbeat, rash, rectal bleeding or inflammation, ringing in
the ears, sensitivity to sunlight, sleepiness, slowed or racing
heartbeat, stiff neck, stiffness, stomach upset or inflammation,
sweating, tongue inflammation, tremor, underactive thyroid,
vertigo, vomiting, weakness, weight gain or loss
Rare
side effects may include:
Abdominal swelling, absence of breathing, agitation, amnesia,
bile duct inflammation, blood clot, blood in the urine, blood
vessel enlargement, bloody diarrhea, breast enlargement, confusion,
deafness, dry skin, eye pain, fluid retention of the face, hangover
effect, heavy periods, hyperactivity, impotence, inflammation
of the small intestine, intestinal bleeding, irregular heartbeat,
liver disorders, nervous disorders, salivary gland enlargement,
shingles, skin discoloration or scaling, slowed breathing, stomach
bleeding, testicular inflammation, thirst, twitching, urinary
incontinence, vaginal discharge, vein inflammation, visual disturbance
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Why
should AcipHex not be prescribed?
If
Rabeprazole gives you an allergic reaction, you will not be
able to use it.
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Special
warnings about AcipHex
If
you have stomach ulcers caused by the H. pylori bacteria, AcipHex
could make the condition slightly worse. The doctor may order
a test for H. pylori before prescribing this drug.
Rabeprazole
has not been tested in children under 18 years of age.
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Possible
food and drug interactions
If AcipHex is taken with certain other drugs, the effects of
either could be increase, decreased, or altered. It is especially
important to check with your doctor before combining Rabeprazole
with the following:
-
Cyclosporine (Neoral, Sandimmune)
- Ketoconazole (Nizoral)
- Digoxin (Lanoxin)
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Special
information
The effects of AcipHex during pregnancy have not been adequately
studied. If you are pregnant or plan to become pregnant, inform
your doctor immediately. Rabeprazole may appear in breast milk
and should not be taken while you're breastfeeding.
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Recommended
dosage
ADULTS
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Gastroesophageal Reflux Disease (GERD)
The
usual dose is 20 milligrams once a day for 4 to 8 weeks. For
patients who have not healed after 8 weeks, the doctor may prescribe
an additional 8-week course of AcipHex therapy.
To
Prevent a Relapse of GERD
The
usual dose is 20 milligrams once a day.
Duodenal
Ulcer
The
usual dose is 20 milligrams taken once daily after the morning
meal for a period of up to 4 weeks. Some people may require
an additional 4 weeks of treatment.
Zollinger-Ellison
Syndrome
The
usual starting dose is 60 milligrams once a day, although your
doctor may adjust the dose based on your individual need. Doses
of up to 100 milligrams once a day or 60 milligrams twice a day
are sometimes prescribed.
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Overdosage
Little
is known about AcipHex overdose. However, any medication taken
in excess can have serious consequences. If you suspect an overdose,
seek medical attention immediately. |