Pregnancy—If you become pregnant as a result of using this medicine with menotropins (e.g., Pergonal) or urofollitropin (e.g., Metrodin), there is an increased chance of a multiple pregnancy (for example, twins, triplets).

Children—Pregnyl, when used for treating cryptorchidism (a birth defect where the testes remain inside the body), has caused the sexual organs of some male children to develop too rapidly.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems—The presence of other medical problems may affect the use of Pregnyl. Make sure you tell your doctor if you have any other medical problems, especially:

Pregnyl : Full Prescribing Information

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What special precautions should I follow?

It is very important that your doctor check your progress at regular visits to make sure that the medicine is working and to check for unwanted effects.

For women taking this medicine to become pregnant :

Record your basal body temperature every day if told to do so by your doctor, so that you will know if you have begun to ovulate. It is important that intercourse take place around the time of ovulation to give you the best chance of becoming pregnant. Your doctor will likely want to monitor the development of the ovarian follicle(s) by measuring the amount of estrogen in your bloodstream and by checking the size of the follicle(s) with ultrasound examinations.

What side effects can Pregnyl cause?

Along with its needed effects, a medicine may cause some other effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

For females only
More common
Bloating (mild); stomach or pelvic pain

Less common or rare
Abdominal or stomach pain (severe); bloating (moderate to severe); decreased amount of urine; feeling of indigestion; nausea, vomiting, or diarrhea (continuing or severe); pelvic pain (severe); shortness of breath; swelling of feet or lower legs; weight gain (rapid)

For boys only
Less common
Acne; enlargement of penis and testes ; growth of pubic hair; increase in height (rapid)

What storage conditions are needed for Pregnyl?

Store at 15°-30°C (59°-86°F). Reconstituted solution is stable for 60 days when refrigerated

Pregnyl: Full Prescribing Information